The University has it's main campus in Parkville, Melbourne, Victoria. Many students live within walking distance but there are numerous public transportation options in the city. The University has a Parking and Commuter Services department, offering help and advice on transport. There are several associated rural and regional campuses throughout the Victoria.

Residential colleges Melbourne University has 12 residential colleges in total, seven of which are located in an arc around the cricket oval at the northern edge of the campus, known as College Crescent. The other five are located outside of university grounds. The residential colleges aim to provide accommodation and holistic education experience to university students. Most of the University's residential colleges also admit students from RMIT Universityand Monash University, Parkville campus, with selected colleges also accepting students from the Australian Catholic Universityand Victoria University.

12 residential colleges on campus. The Student Housing Association can help students looking for private accommodation in nearby suburbs, a popular option for students. A cost calculator is provided at http://services.unimelb.edu.au/international/life-and-study/calculator

The University has participated in various sports in its history and has 39 affiliated clubs. Sport is overseen by Melbourne University Sport. The Melbourne University Sports Union was the predecessor to the current Melbourne University Sports Association. Since its inception, the aim of the Union and now the Association is to provide a collective voice for all affiliated sporting clubs on the University campus. In 2004, the Melbourne University Sports Association celebrated its centenary. The Melbourne University Lacrosse Club (MULC) was established in 1883 and is the oldest continually operational lacrosse club in the world. The Melbourne University Cycling Club (MUCyc) is associated with Cycling Australia and competes regularly at local and national races. In 2008 MUCyc won its seventh consecutive AUG championship (2002–2008). The Melbourne University Tennis Club was one of the original five (5) clubs established for the students and staff of the University, with various tennis competitions and social tennis events held on campus as early as 1882.